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2017 (v.25 no.3)

Translational and Clinical Pharmacology

Korean Society for Clinical Pharmacology and Therapeutics
ISSN: 2289-0882

  • Pharmacometric models simulation using NONMEM, Berkeley Madonna and R

    Wan-Su Park

    TCP | v.25, no.3, pp.125-133, Sep, 2017


    In this tutorial, we introduce a differential equation simulation model for use in pharmacometrics involving NONMEM, Berkeley Madonna, and R. We report components of the simulation code and similarities/differences between software, rather than how to use each software. Depending on the purpose of the simulation, an appropriate tool can be selected for effective communication.


    NONMEM, Berkeley Madonna, R, Pharmacometrics, Simulation